Functional RNA Analysis Project

We have been conducting research mainly related to RNA molecular biology and molecular evolution by combining bioinformatics and experimental biology. A typical example is the systematic discovery of functional RNAs such as long non-coding RNAs and microRNAs. Furthermore, we contributed to the discovery of disrupted transfer RNA (tRNA) genes and tRNA-like genes. In parallel with these functional RNA studies, we also report biochemical analysis and molecular evolution of enzymes involved in the regulation of RNA molecules.

Project HP URL：https://k-ris.keio.ac.jp/html/100012576_ja.html
Publication

1. RNA 28:1041-1057. (2022)
2. Genome Biol Evol 11:2713-2726. (2019)
3. RNA Biol 14:206-218. (2017)
4. Mol Biol Evol 33:530-540. (2016)
5. RNA 21:230-242. (2015)
6. Nucleic Acids Res 40:3653-3662. (2012)
7. Nucleic Acids Res 39:9695-9704. (2011)
8. Proc Natl Acad Sci U S A 106:2683-2687. (2009)
9. Mol Biol Evol 25:2709-2716. (2008)
10. Genome Res 13:1301-1306. (2003)

Akio Kanai
Professor