Institute for Advanced Biosciences, Keio UniversityInstitute for Advanced Biosciences, Keio University

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Molecular Oncology Project

分子腫瘍グループ/Molecular Oncology Project

Most cancers originate from epithelial cells. Normal epithelial cells share a common property called "cell polarity," but abnormalities in cell polarity are frequently observed in cancer tissues. Our research group focuses on cell polarity, the essential feature of epithelial cells, to clarify why cancer cells have abnormalities in cell polarity and in the proteins that regulate cell polarity. Our research group aims to understand cancer cells from a biological perspective by addressing the question. We believe that we can develop new cancer treatments and therapeutic drugs if we truly understand cancer cells as living organisms.


Publication

  1. J. Exp. Med. 207:2157-2174.(2010)
  2. BBA Reviews on Cancer 1869:103-116. (2018)
  3. Nature 569:275-279. (2019)
  4. Commun. Biol. 5:403.(2022)
齊藤 康弘 特任講師

Yasuhiro Saito
Project Associate Professor

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