Institute for Advanced Biosciences, Keio UniversityInstitute for Advanced Biosciences, Keio University

Research Projects

HOME Research Projects Bacterial regulatory RNA project

Bacterial regulatory RNA project

微生物制御RNAプロジェクト/Bacterial regulatory RNA project


Microorganisms inhabit diverse environments including soil, rivers, and animals. To respond to environmental cues, gene expression is regulated at multiple levels. Among the years, regulation at the RNA level, such as transcription termination, translation, and mRNA stability, has been found, however some of the molecular mechanisms and regulatory factors are poorly understood. Our project will elucidate the functions of small regulatory RNAs and RNA-binding proteins as regulatory factors in Escherichia coli, leading to the establishment of an RNA technology platform for microbial control.


Publication

  1. mBio. 13:e0237122.(2022)

  2. Elife 11:e82411.(2022)
  3. RNA 25:264-276.(2019)
  4. Front Cell Infect Microbiol. 9:201.(2019)
  5. RNA 23:1419-1431.(2017)
  6. J Immunol. 197:1298-1307. (2016)
  7. RNA 21:1490-1501. (2015)
  8. RNA 18:1062-1074. (2012)
  9. J Biol Chem. 287:32485-32493.(2012)
  10. Proc Natl Acad Sci U SA. 108:13059-13064.(2011)
森田 鉄兵 特任講師

Teppei Morita
Project Associate Professor

TOPへ